CJC-1295 no DAC

Basic Information

– Sequence: 29 amino acids; a synthetic analog of GHRH (growth hormone-releasing hormone) derived from natural GHRH (1-29) with four site-specific mutations: D-Ala²、Gln⁸、Ala¹⁵、Leu²⁷; C-terminal amidation to resist degradation by DPP-IV

– Molecular weight: 3367.9 Da

– Half-life: ~30 min (free peptide in vivo, without the albumin-binding group DAC)

– Target: Pituitary GHRH receptor; stimulates GH secretion in a pulsatile manner, more closely mimicking the body’s endogenous GH secretion pattern; often used in combination with Ipamorelin (GHRP) for synergistic studies

Dissolution and Storage (Laboratory Procedures)

1. Solvent: BAC water / AA water (sterile acetic acid water), standard lyophilized peptide reconstitution system

2. Refrigeration after reconstitution: Can be stored at 2–8°C for approximately 2–4 weeks; for long-term storage, aliquot and freeze at -20°C, avoiding repeated freeze-thaw cycles

3. Solubility: Good water solubility

Research Combinations

Most Classic Combination: CJC-1295 No DAC + Ipamorelin

– Mod GRF (GHRH receptor agonist) amplifies pulsatile GH release from the pituitary gland

– Ipamorelin (GHSR agonist) stimulates GH secretion; the two exhibit synergistic effects and are a commonly used combination in GH axis research Important Notes

1. This substance is for research purposes only and must not be injected into humans.

2. As a growth hormone-releasing peptide, it is classified as a banned substance in sports competitions.

3. All information is provided solely as laboratory chemical/pharmacological data and does not constitute any guidance on drug use.