Cortagen

Cortagen (abbreviated as AEDP), a synthetic tetrapeptide bioregulator
CAS:335591‑03‑2, Amino acid sequence: Ala‑Glu‑Asp‑Pro
Key pharmacological functions
No GIP/GLP‑1/GCGR agonistic activity; its mechanism relies on epigenetic regulation and modulation of chromatin and gene expression
Cerebral cortical cells: upregulates BDNF and NGF neurotrophic factors, promotes synaptogenesis and neural plasticity
Antioxidant and anti‑inflammatory effects: reduces neuronal oxidative stress, inhibits neuronal apoptosis and balances central inflammatory response
Peripheral nerves: accelerates damaged nerve repair and improves nerve conduction function
Overall effects: neuroprotection, improved memory and cognitive performance, delayed neural aging, supports functional recovery after brain tissue injury